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quinupristin/dalfopristin will improve the stage or outcome of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.two The 50 %-lifetime of quinupristin and its metabolites is about 3 several hours, Whilst the 50 percent-lifetime of dalfopristin and its metabolites is roughly just one hour.quinupristi